Betamethasone + Gentamicin + Zinc Sulfate Topical
Indications
Betamethasone + Gentamicin + Zinc Sulfate Topical is used for:
Eczema, atopic dermatitis, contact dermatitis, psoriasis
Adult Dose
Topical
Adult
Cream/Lotion: Apply sparingly 2-3 times daily.
Child Dose
Renal Dose
Administration
Topical Administration
Use medium to very high potency for less than 2 weeks to reduce local and systemic side effects
Contra Indications
Underlying infection, Hypersensitivity
Precautions
Chronic topical corticosteroid therapy may interfere with growth and development in children.
Lactation: It is not known whether topical corticosteroid use could result in sufficient systemic absorption to produce detectable quantities in human milk; use with caution.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Betamethasone + Gentamicin + Zinc Sulfate Topical :
Application site reactions (burning, irritation, itching and redness). Dermal atrophy, local irritation, folliculitis, hypertrichosis, burning, dry skin, pigmentation changes
Mechanism of Action
Betamethasone is a corticosteroid with mainly glucocorticoid activity. It prevents and controls inflammation by controlling the rate of protein synthesis, depressing the migration of polymorphonuclear leukocytes and fibroblasts, and reversing capillary permeability and lysosomal stabilisation.
Gentamicin is an aminoglycoside that has broad spectrum bactericidal activity; it is active against a wide variety of pathogenic gram-negative and gram-positive bacteria.