Carisoprodol
Indications
Carisoprodol is used for:
Painful muscle spasm associated with musculoskeletal conditions
Adult Dose
Oral
Painful muscle spasm associated with musculoskeletal conditions
Adult: 350 mg 3-4 times daily for up to 2-3 wk.
Elderly: Half of the usual dose.
Child Dose
Musculoskeletal Conditions
<16 years: Not recommended
>16 years: 250-350 mg q8hr and HS
Renal Dose
Administration
May be taken with or without food.
Contra Indications
Acute intermittent porphyria, hypersensitivity. Lactation.
Precautions
Renal and hepatic failure. Pregnancy. Should be used with caution in addiction prone individuals.
Lactation: Enters breast milk; use with caution
Pregnancy-Lactation
Interactions
Potentially Fatal: Potentiates alcohol and other CNS depressants.
Adverse Effects
Side effects of Carisoprodol :
>10%
Drowsiness (13-17%)
1-10%
Dizziness (7-8%),Headache (3-5%)
Frequency Not Defined
Orthostatic hypotension,Syncope,Tachycardia,Agitation,Irritability,Depression,Allergic/idiosyncratic reactions (pruritus, rash, dizziness, etc),Epigastric distress,N/V,Facial flushing,Weakness
Mechanism of Action
Carisoprodol blocks interneuronal synaptic activity in the descending reticular formation and spinal cord resulting in skeletal muscle relaxation.