Choline Salicylate solution oral prep
Indications
Choline Salicylate solution oral prep is used for:
Adult Dose
Buccal
Mouth lesions
Adult: Apply 8.7% gel on affected area.
Child Dose
Renal Dose
Administration
Contra Indications
Haemophilia, haemorrhagic disorders, gout, history of hypersensitivity to salicylates. Severe renal or hepatic impairment; childn <12 yrs. Pregnancy and lactation.
Precautions
Peptic ulcers, errosive gastritis; asthma, allergic disorders; renal and hepatic impairment; dehydrated patients; uncontrolled hypertension; elderly.
Pregnancy-Lactation
Interactions
Increased toxicity of warfarin. Antacids may reduce salicylate effects. Increased risk of GI bleeding when used with corticosteroids.
Adverse Effects
Side effects of Choline Salicylate solution oral prep :
GI disorders, fatigue, hypersensitivity reactions, skin eruptions, haemolytic anaemia, weakness, dyspnoea; local irritation (rectally); Reye's syndrome.
Potentially Fatal: Paroxysmal bronchospasm; hepatotoxicity; renal impairment; thrombocytopenia, iron-deficiency anaemia, occult bleeding, leukopenia; mild chronic salicylate intoxication.
Mechanism of Action
Choline salicylate alleviates pain by inhibition of prostaglandin synthesis and reduce fever by acting on the hypothalamus heat-regulating center. It also blocks the generation of impulses.