Chondroitin + Glucosamine
Indications
Chondroitin + Glucosamine is used for:
Osteoarthritis, rheumatoid arthritis, sport injuries, migraine, different skin problems (e.g., psoriasis), vascular complications (e. g., atherosclerosis), kidney stones, and inflammatory bowel disease (e.g., ulcerative colitis, leaky gut syndrome), Nutritional supplement, Dietary supplement
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Proven hypersensitivity (e. g. allergic to shellfish or sulfur) to Glucosamine and Chondroitin is a contraindication.
Precautions
Diabetic patients, patients on heparin. Pregnancy and lactation.
Lactation: Unknown; not recommended
Pregnancy-Lactation
Interactions
May increase insulin resistance & affect glucose tolerance; reduce antidiabetic agent effectiveness. Increase INR value w/ warfarin & potentiates anticoagulant effect.
Adverse Effects
Side effects of Chondroitin + Glucosamine :
Chondroitin Sulfate: Allergic reactions, alopecia, constipation, diarrhea, edema, (eyelid/lower limb), epigastric pain, extrasystoles, nausea.
Glucosamine Sulfate: Possible poor glycemic control in diabetics; monitor blood glucose, Increased intraocular pressure (see Cautions), Constipation, Diarrhea, Drowsiness, Headache, Heartburn, Hyperinsulinemia, Nausea, Skin reactions
Mechanism of Action
Glucosamine Sulphate: A special ingredient to help keep joints in good shape. Glucosamine is naturally required by the body for the production of collagen to cushion the joints (cartilage) and synovial fluid which bathes and lubricates them. It is present in the formulation in the preferred potassium form, with minerals for improved absorption. Glucosamine stimulates the production of proteoglycans and increases sulfate uptake by articular cartilage.
Chondroitin Sulphate: Helps form the proteins that maintain cartilage elasticity and works synergistically with glucosamine to help maintain joint health. Chondroitin is cartilage derivative; component of hyaline cartilage matrix that may repair cartilage & reduce synovial inflammation.