Citric acid + Sodium citrate

Indications

Citric acid + Sodium citrate is used for: Urine Alkalinization, Prevention of Nephrolithiasis

Adult Dose

Urine Alkalinization, Prevention of Nephrolithiasis 10-30 mL diluted in up to 6 oz water/juice PO PC & HS PRN

Child Dose

Urine Alkalinization, Prevention of Nephrolithiasis <2 years: Based on physician's discretion >2 years: 5-15 mL diluted in 30-90 mL of water/juice PO PC & HS PRN

Renal Dose

Administration

Contra Indications

Hypersensitivity to drug or component of the formulation Severe renal impairment Sodium-restricted diet

Precautions

Use with caution in high BP, kidney or liver disease, cardiac failure, toxemia of pregnancy, peripheral/pulmonary edema, shock, or the severely ill Do not dilute in tomato juice

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Citric acid + Sodium citrate : Frequency Not Defined Diarrhea Nausea Tetany Metabolic alkalosis Vomiting Stomach pain Fluid retention

Mechanism of Action

Alkalinizes urine; citrate binds with urinary calcium