Cyclandelate
Indications
Cyclandelate is used for:
Cerebrovascular disorders, Peripheral vascular disease
Adult Dose
Oral
Cerebrovascular disorders, Peripheral vascular disease
Adult: Initial: Up to 2 g daily. Maintenance: 800-1200 mg daily. Max: 2 g/day in divided doses.
Max Dosage: 2 g daily in divided doses.
Child Dose
Renal Dose
Administration
Contra Indications
Acute phase of cerebrovascular accidents.
Precautions
Severe obliterative coronary artery disease; cerebrovascular disease.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Cyclandelate :
Flushes, GI upset, nausea, tingling, tachycardia, sweating, dizziness, headache.
Mechanism of Action
Cyclandelate is a vasodilator more potent than papaverine. It has direct action on the plain muscle and there is no effect on the adrenergic tone.