Eflornithine topical
Indications
Eflornithine topical is used for:
Reduction of Facial Hair in Women
Adult Dose
Reduction of Facial Hair in Women
Apply to affected area twice daily at least 8 hours apart
Child Dose
Reduction of Facial Hair in Women
<12 years: Safety & efficacy not established
>12 years: Apply to affected area twice daily at least 8 hours apart
Renal Dose
Administration
Contra Indications
Hypersensitivity
Precautions
Discontinue if sensitivity occurs
Lactation: Not known whether distributed into breast milk; use caution
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Eflornithine topical :
Frequency Not Defined
Acne
Pseudofolliculitis barbae
Burning
Stinging
Dry, and/or tingling skin
Erythema
Anorexia
Neutropenia
Injection site reaction
Myalgia/arthralgia
Rash
Pruritus
Alopecia
Fever
Arrhythmia
Chest pain
Headache
Dizziness
Dyspepsia
Mechanism of Action
May inhibit ornithine decarboxylase (ODC), an enzyme that catalyzes biosynthesis of intracellular polyamines required for cell division & differentiation, which in turn can affect hair growth