Ergoloid Mesylates
Indications
Ergoloid Mesylates is used for:
Used as peripheral vasodilators.
Age-Related Mental Decline & Alzheimer's Dementia
Adult Dose
Adult
Age-Related Mental Decline & Alzheimer's Dementia
1 mg PO q8hr
May administer up to 4.5-12 mg/day therapeutic trial should be 6 months in duration
Child Dose
Renal Dose
Administration
Contra Indications
Hypersensitivity, psychosis;
Precautions
Consider other CNS disease before starting
CYP3A4 inhibitors (azole anifungals, protease inhibitors, macrolide antibiotics)
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Ergoloid Mesylates :
Flushing
Headache
Rash
Nausea
Vomiting
Nasal congestion
Blurred vision
Bradycardia or bradyarrhythmia
Orthostatic hypotension
Mechanism of Action
Contains derivatives of three naturally occurring ergot alkaloids which have some peripheral alpha blocking activity and also depress CNS vasomotor nerve activity resulting in slight decrease in BP and HR; mechanism of action in dementia is largely unknown