Fluocinolone + Gentamicin Topical
Indications
Fluocinolone + Gentamicin Topical is used for:
Bacterial skin infections, eczema, seborrheic dermatitis, contact dermatitis
Adult Dose
Adult: Topical cream/oint: Apply 2-3 times/day.
Child Dose
Renal Dose
Administration
Contra Indications
Primary infectious (bacterial, viral, fungal) ulcers, hypersensitivity, acne vulgaris. Neonates.
Precautions
Children, elderly, hepatic failure. Prolonged use on the face; contact with eyes. Pregnancy, lactation.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Fluocinolone + Gentamicin Topical :
Dry skin, pruritus, irritation, mild to moderate transient burning/stinging. Local atrophic changes in the skin (prolonged & intensive treatment). Hypercorticism (systemic absorption on prolonged use). Itching, folliculitis, hypertrichoses, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of skin, secondary infections, striae & miliaria.
Mechanism of Action
Fluocinolone acetonide is a synthetic fluorinated corticosteroid that is used topically for its anti-inflammatory, anti-pruritic and vasoconstrictive properties.
Gentamicin is an aminoglycoside that binds to 30s and 50s ribosomal subunits of susceptible bacteria disrupting protein synthesis, thus rendering the bacterial cell membrane defective.