Glucosamine

Indications

Glucosamine is used for: Rheumatoid arthritis, Osteoarthritis, Nutritional supplement, Low back pain, Acute gout, Degenerative joint disease

Adult Dose

Oral Osteoarthritis; Rheumatoid arthritis Adult: 500 mg 3-4 times daily. Max Dosage: 1500 mg/day.

Child Dose

Renal Dose

Administration

Should be taken with food. Preferably taken at meals.

Contra Indications

Allergy to shellfish.

Precautions

Diabetic patients, patients on heparin. Pregnancy and lactation.

Pregnancy-Lactation

Interactions

Glucosamine: May reduce effect of antidiabetic agents, doxorubicin, etoposide, tenoposide. May enhance anticoagulant activity of warfarin.

Adverse Effects

Side effects of Glucosamine : Possible poor glycemic control in diabetics; monitor blood glucose,Increased intraocular pressure,Constipation,Diarrhea,Drowsiness,Headache,Heartburn,Hyperinsulinemia,Nausea,Skin reactions

Mechanism of Action

Glucosamine stimulates the production of proteoglycans and increases sulfate uptake by articular cartilage.