Hydrocortisone + Naphazoline nasal prep
Indications
Hydrocortisone + Naphazoline nasal prep is used for:
Reduce the nasal congestion and swelling in the nasal passages. Conditions for which it is commonly used include hay fever (seasonal allergic rhinitis), perennial allergic rhinitis (year round nasal irritation), vasomotor rhinitis
Adult Dose
Nasal Drops
Adult: Instilled directly into the nose 2 to 3 drops (into both nostrils) 2 to 3 times per day.
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
These drops could trigger rhinitis medicamentosa if used for an extended period of time.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Hydrocortisone + Naphazoline nasal prep :
Crusting
Sneezing
Mild irritation
Dryness inside the nose
Mucus discharge from the nose
Mechanism of Action
Naphazoline is an alpha adrenergic receptor agonist which causes vasoconstriction by stimulating arterioles of the conjunctiva and nasal mucosa thus reducing swelling, redness and discomfort when applied to mucous membranes.
Hydrocortisone is a corticosteroid used for its anti-inflammatory and immunosuppressive effects. Its anti-inflammatory action is due to the suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability. It may also be used as replacement therapy in adrenocortical insufficiency.