Iodine 2.5 %
Indications
Iodine 2.5 % is used for:
Wound and ulcer cleansing, Superficial wounds
Adult Dose
Topical/Cutaneous
Minor, superficial skin wounds
Adult: As solution/ointment: Apply small amount to the affected area 1-3 times daily.
Child Dose
Topical/Cutaneous
Minor, superficial skin wounds
Child: As solution/ointment: Apply small amount to the affected area 1-3 times daily.
Renal Dose
Administration
Contra Indications
Hypersensitivity. Acute bronchitis (potassium iodide).
Precautions
Children. Adult >45 yr. Topical applications should not be covered with occlusive dressings. Nodular goitre. Renal impairment. Hypocomplemetemic vasculitis. TB (potassium iodide). Pregnancy and lactation.
Pregnancy-Lactation
Interactions
Additive or synergistic hypothyroid effect with lithium salts, antithyroid agents. Additive hyperkalaemia with combined use of potassium iodide and potassium-containing drugs or potassium-sparing diuretics.
Adverse Effects
Side effects of Iodine 2.5 % :
Topical: Hypersensitivity reactions (urticaria, angioedema, cutaneous haemorrhage, purpura, fever, arthralgia, lymphadenopathy, eosinophilia); goitre, hypothyroidism and hyperthyroidism. Iodism on prolonged use (metallic taste, increased salivation, swelling and inflammation of throat, swollen and irritated eyes, pulmonary oedema, nausea, vomiting, diarrhoea).
Potentially Fatal: Fatal periarteritis, ioderma.
Mechanism of Action
Topical iodine acts as a local irritant and as a germicide active against gram-positive and gram-negative bacteria, fungi, trichomonas, cysts, viruses and some spores.