Iodochlorhydroxyquinoline (Clioquinol) topical

Indications

Iodochlorhydroxyquinoline (Clioquinol) topical is used for: Skin fungal infections

Adult Dose

Topical/Cutaneous Skin fungal infections Adult: Apply cream or ointment 2-4 times daily onto affected areas (cleansed and dried thoroughly). Treatment continued for 4 wk for athlete's foot or ringworm and for 2 wk when treating jock itch.

Child Dose

Renal Dose

Administration

Contra Indications

Hypersensitivity; child <2 yr. Do not apply on eczematous or broken skin and perforated tympanic membrane.

Precautions

Can stain fabric and skin. Avoid contact with eyes; avoid prolonged use. Not effective in the treatment of fungal infections of the scalp or nails. Discontinue if local irritation, rash, sensitivity occur.

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Iodochlorhydroxyquinoline (Clioquinol) topical : Severe irritation or hypersensitivity. Cross-sensitivity with other halogenated hydroxyquinolines. May discolour fair hair. Potentially Fatal: May cause severe neurotoxicity.

Mechanism of Action

Clioquinol is a halogenated hydroxyquinoline with antibacterial and antifungal activity.