Ioversol
Indications
Ioversol is used for:
Peripheral and coronary arteriography and left ventriculography,Intravenous excretory urography,Angiography
Adult Dose
Radiographic Body Imaging
Usual: 50-150 mL IV OR 100-250 mL IV of (240 mg/mL)
25-75 mL IV OR 50-150 mL IV infusion; not to exceed 150 mL
For 240 mg/mL: 35-100 mL IV OR 70-200 mL IV infusion; not to exceed 250 mL
IV-DSA
30-50 mL IV, repeat PRN; NMT 250 mL
Administration
Central catheter: inject at 10-30 mL/sec
Peripheral: inject at 12-20 mL/sec
Flush vein immediately after injection w/ 20-25 mL of NS or D5W
IV Urography
50-75 mL IV OR
75-100 mL IV of (240 mg/mL)
Child Dose
Radiographic Body Imaging
1-3 mL/kg IV (usual: 2 mL/kg)
IV Urography
0.5-3 mL/kg IV (usual 1-1.5 mL/kg); not to exceed 3 mL/kg
Renal Dose
Administration
Contra Indications
Hypersensitivity.
Precautions
Diagnostic procedures which involve the use of iodinated intravascular contrast agents should be carried out under the direction of personnel skilled and experienced in the particular procedure to be performed. A fully equipped emergency cart, or equivalent supplies and equipment, and personnel competent in recognizing and treating adverse reactions of all types should always be available. Since severe delayed reactions have been known to occur, emergency facilities and competent personnel should be available for at least 30 to 60 minutes after administration.
Lactation: not known, use caution
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Ioversol :
Usually mild to moderate, of short duration and resolve spontaneously (without treatment). However, serious, life-threatening and fatal reactions, mostly of cardiovascular origin, have been associated with the administration of iodine-containing contrast media.
Injections of contrast media are often associated with sensations of warmth and pain. In controlled double-blind clinical studies, significantly less warmth and pain were associated with the injection than with iothalamate meglumine, diatrizoate meglumine, and diatrizoate meglumine and diatrizoate sodium.