Lactulose + Ispaghula

Indications

Lactulose + Ispaghula is used for: Treatment of Chronic constipation, Hepatic encephalopathy

Adult Dose

Oral Adult 2-3 tsf 3-4 times daily

Child Dose

Renal Dose

Administration

Contra Indications

Galactosaemia, GI obstruction, digestive perforation or risk of digestive perforation. Patient on low galactose diet.

Precautions

Low galactose diet This medicine should be administered with extreme caution in patients requiring a low galactose diet. This dietary change is usually recommended for patients having a rare genetic disorder known as galactosemia. Diabetes This medicine should be used with caution if you are diabetic. Appropriate dose adjustment and more frequent checking of the blood glucose levels is recommended while taking this medicine. Electrolyte imbalance Use of this medicine can cause an imbalance in the levels of potassium, magnesium, and other electrolytes in the body. It should be used with caution in children and patients suffering from any electrolyte imbalances. Other laxatives This medicine is not recommended for use along with other laxatives especially when treating the symptoms of liver failure.

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Lactulose + Ispaghula : Diarrhea Excessive bowel activity Nausea or Vomiting Abdominal pain and cramps Belching Flatulence Low potassium and magnesium

Mechanism of Action

Lactulose promotes peristalsis by producing an osmotic effect in the colon w/ resultant distention. In hepatic encephalopathy, it reduces absorption of ammonium ions and toxic nitrogenous compounds, resulting in reduced blood ammonia concentrations.