Latanoprost 0.005% Eye prep
Indications
Latanoprost 0.005% Eye prep is used for:
Open-angle glaucoma, Ocular HTN
Adult Dose
Adult:
As 0.005% eye drop:
Instill 1 drop in affected eye once daily in every evening.
Child Dose
Safety and efficacy not established
Renal Dose
Administration
Contra Indications
Hypersensitivity.
Precautions
Do not use within 5 min of thiomersal-containing preparations. Aphakia or pseudophakia with torn posterior lens cap or anterior chamber lenses; risk factors for cystoid macular oedema; brittle or severe asthma; history of intraocular inflammation; inflammatory, neovascular, angle-closure or congenital glaucoma; pregnancy, lactation. Remove contact lenses during use.
Lactation: not known whether distributed into milk; use with caution
Pregnancy-Lactation
Interactions
Paradoxical elevations in IOP w/ other prostaglandins, prostaglandin analogs or prostaglandin derivatives.
Adverse Effects
Side effects of Latanoprost 0.005% Eye prep :
>10%
Increase in brown pigmentation of the iris (15.5%),Blurred vision (5-15%),Burning and stinging (5-15%),Foreign body sensation (5-15%),Itching (5-15%),Punctate epithelial keratopathy (5-15%),Conjunctival hyperemia (5-15%)
1-10%
Upper respiratory tract infection/cold/flu (4%),Dry eye (1-4%),Excessive tearing (1-4%),Eye pain (1-4%),Lid crusting (1-4%),Lid edema (1-4%),Lid erythema (1-4%),Lid discomfort/pain (1-4%),Photophobia (1-4%),Chest pain/angina pectoris (1-2%),Muscle/joint/back pain (1-2%),Rash/allergic skin reactions (1-2%)
<1%
Conjunctivitis,Diplopia,Discharge from the eye
Frequency Not Defined
Dizziness,Headache
Mechanism of Action
Latanoprost, a synthetic analogue of prostaglandin F2alpha, reduces the IOP by increasing the outflow of aqueous humour.