Latanoprost 0.005% Eye prep

Indications

Latanoprost 0.005% Eye prep is used for: Open-angle glaucoma, Ocular HTN

Adult Dose

Adult: As 0.005% eye drop: Instill 1 drop in affected eye once daily in every evening.

Child Dose

Safety and efficacy not established

Renal Dose

Administration

Contra Indications

Hypersensitivity.

Precautions

Do not use within 5 min of thiomersal-containing preparations. Aphakia or pseudophakia with torn posterior lens cap or anterior chamber lenses; risk factors for cystoid macular oedema; brittle or severe asthma; history of intraocular inflammation; inflammatory, neovascular, angle-closure or congenital glaucoma; pregnancy, lactation. Remove contact lenses during use. Lactation: not known whether distributed into milk; use with caution

Pregnancy-Lactation

Interactions

Paradoxical elevations in IOP w/ other prostaglandins, prostaglandin analogs or prostaglandin derivatives.

Adverse Effects

Side effects of Latanoprost 0.005% Eye prep : >10% Increase in brown pigmentation of the iris (15.5%),Blurred vision (5-15%),Burning and stinging (5-15%),Foreign body sensation (5-15%),Itching (5-15%),Punctate epithelial keratopathy (5-15%),Conjunctival hyperemia (5-15%) 1-10% Upper respiratory tract infection/cold/flu (4%),Dry eye (1-4%),Excessive tearing (1-4%),Eye pain (1-4%),Lid crusting (1-4%),Lid edema (1-4%),Lid erythema (1-4%),Lid discomfort/pain (1-4%),Photophobia (1-4%),Chest pain/angina pectoris (1-2%),Muscle/joint/back pain (1-2%),Rash/allergic skin reactions (1-2%) <1% Conjunctivitis,Diplopia,Discharge from the eye Frequency Not Defined Dizziness,Headache

Mechanism of Action

Latanoprost, a synthetic analogue of prostaglandin F2alpha, reduces the IOP by increasing the outflow of aqueous humour.