Meningococcal polysaccharide ACWY Vaccine
Indications
Meningococcal polysaccharide ACWY Vaccine is used for:
Meningococcal meningitis and septicaemia, Meningococcal Pneumonia, Meningococcemia
Adult Dose
Child Dose
Renal Dose
Administration
Administer IM only; do not administer IV, SC, or ID
Give IM injection, preferably into the anterolateral aspect of the thigh in infants or into the deltoid muscle in toddlers, adolescents, and adults
Contra Indications
Severe allergic reaction (eg, anaphylaxis) after a previous dose of a meningococcal capsular polysaccharide-, diphtheria toxoid- or CRM197-containing vaccine, or to any component.
Precautions
Guillain-Barre syndrome. Preventing & managing allergic vaccine reactions. Thrombocytopenia or bleeding disorders. Immunocompromised person. Pregnancy & lactation.
Pregnancy-Lactation
Interactions
This can be administered at the same time as other vaccines. Different injectable vaccines should always be administered at a different injection site.
Incompatibilities: In the absence of compatibility studies, this vaccine must not be mixed with other medicinal products.
Adverse Effects
Side effects of Meningococcal polysaccharide ACWY Vaccine :
Local and systemic adverse reactions especially febrile reactions may be encountered more frequently in children than in adults. Irritability, drowsiness, headache, gastrointestinal symptoms e.g. nau sea, vomiting and diarrhoea, local axillary lymphadenopathy. Very common: erythema, induration, tenderness, pain and redness at the injection site, fatigue, malaise.
Mechanism of Action
Meningococcal serogroup A, C, Y and W-135 capsular polysaccharide antigens individually conjugated to diphtheria toxoid protein carrier..
These products convey active immunity via stimulation of production of endogenously produced antibodies.