Mosapride
Indications
Mosapride is used for:
Disorders associated with reduced gastrointestinal motility
Adult Dose
Oral
Disorders associated with reduced gastrointestinal motility
Adult: As anhydrous citrate: 5 mg tid.
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Continuous admin of this drug is not recommended if no improvement in GI symptoms is observed after 2 wk of admin. Elderly, renal impairment, hepatic impairment.
Pregnancy-Lactation
Interactions
Mosapride concentration increased by erythromycin. May increase risk of QT prolongation with QT prolonging drugs.
Adverse Effects
Side effects of Mosapride :
Diarrhoea, abdominal pain; dizziness; constipation; headache; insomnia; nausea.
Mechanism of Action
Mosapride is a 5-HT4 receptor agonist which increases the release of acetylcholine and stimulates GI motility. It also has 5-HT3 antagonist properties.