Oxiconazole 1% Topical

Indications

Oxiconazole 1% Topical is used for: Tinea pedis, Tinea cruris, Tinea corporis, Pityriasis versicolor

Adult Dose

Topical/Cutaneous Tinea cruris; Tinea corporis; Tinea pedis Adult: Apply 1% cream once or bid. Duration of treatment: 2 wk for tinea corporis and tinea cruris or 1 mth for tinea pedis. Pityriasis versicolor Adult: As 1% cream: Apply to affected areas once daily for 2 wk.

Child Dose

Renal Dose

Administration

Contra Indications

Hypersensitivity.

Precautions

Pregnancy and lactation. Avoid contact with eyes. Discontinue if irritation or sensitisation occurs. Cross-sensitisation with other imidazole derivatives may occur. Lactation: distributed into milk; use with caution in nursing women

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Oxiconazole 1% Topical : 1-10% Pruritus (1-2%),Burning (1-2%) <1% Irritation,Stinging,Erythema,Rash,Folliculitis,Papules,Nodules,Maceration,Fissuring

Mechanism of Action

Oxiconazole, a synthetic azole antifungal, is usually fungistatic but may be fungicidal in high concentrations. It exerts its antifungal activity by interfering w/ ergosterol synthesis and altering cellular membranes. It also has some antibacterial activity against aerobic gm+ve organisms.