Pemirolast Potassium 0.1% Eye prep

Indications

Pemirolast Potassium 0.1% Eye prep is used for: Allergic conjunctivitis

Adult Dose

Ophthalmic Prophylaxis of allergic conjunctivitis Adult: As 0.1% ophthalmic solution: Instill 1-2 drops into the affected eye(s) 4 times daily.

Child Dose

Ophthalmic Prophylaxis of allergic conjunctivitis Child: >3 yr: As 0.1% ophthalmic solution: Instill 1-2 drops into the affected eye(s) 4 times daily.

Renal Dose

Administration

Contra Indications

Contraindicated in patients with previously demonstrated hypersensitivity to any of the ingredients of this product.

Precautions

Not for treatment of contact lens-related irritation. Contact lens should be removed prior to drug admin and reinserted only at least 10 minutes after application. Safety and efficacy have not been established in children <3 yr. Pregnancy and lactation. Lactation: Distributed in breast milk; caution advised

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Pemirolast Potassium 0.1% Eye prep : 1-10% Burning,Dry eyes,Foreign body sensation,Ocular discomfort,Allergy,Bronchitis,Cough,Sneezing,Nasal congestion

Mechanism of Action

Pemirolast is a mast cell stabiliser that inhibits the in vivo Type I immediate hypersensitivity reaction. It inhibits chemotaxis of eosinophils into the ocular tissue and blocks the release of mediators. It is also reported to prevent calcium influx into mast cells following antigen stimulation. It has also been used in the treatment of chronic asthma and prophylaxis of allergic rhinitis.