Placenta Extracts topical
Indications
Placenta Extracts topical is used for:
Topical Wound Healer (Chronic non-healing wounds).
Cervical erosion; cervicitis; vaginitis.
Adult Dose
Topical Gel
Adult
Apply 1-2 g bd-tds
Child Dose
Renal Dose
Administration
Contra Indications
Hypersenstivity.
Precautions
This medicine is for external use only. Avoid direct contact of cream or gel with your eyes.
Wash hands thoroughly prior to application. Observe strict personal hygiene to prevent re-infection. Signs of increased irritation eg, redness, itching, burning should be reported to a doctor. Time treatment so as to avoid menstrual period & finish before onset of menstruation. Avoid sources of infection or re-infection. Apply after bath or shower. Avoid wearing tight, restrictive clothing. Do not douche or use tampons during the course of treatment.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Placenta Extracts topical :
Mechanism of Action
This is an activator of cellular biosynthesis that favors the anabolic phase and tissue-repairing. The presence of nucleotides like PDRNs and NADPH, facilitates the anti-inflammatory and wound healing actions as well. Wound healing is rather by reorganization than regeneration Placentrex facilitates Nitric Oxide (NO) mediated wound healing and repair, helps to kill bacteria, has debridement action on necrotic tissue, causes cellular migration, promotes new blood vessel formation, increases collagen deposits, dilatation of blood vessels , thus increases the viability of skin flaps.
Fibronectin type III is involved in cell adhesion. It also stabilizes trypsin which is responsible for the debridement of wound.Ubiquitin like peptide in Placentrex has collagenase like action breaking down faulty collagen. This property is essential for the remodeling phase of wound healing. The drug also enhances body immunity.