Plasma Volume Substitute

Indications

Plasma Volume Substitute is used for: Dehydration, Fluid replacement, Hypovolemic shock, loss of blood & plasma eg due to trauma, burns, autologous blood or plasma donation before an operation. For filling the heart-lung machine.

Adult Dose

Adult Shock prophylaxis 500-1,500 mL, approx 20 mL/kg/day. Vol-deficiency shock Max: 2,000 mL. In emergencies: Vol as required. In case of long-term maintenance of plasma vol, infusion should not cause the hematocrit to fall below 30 vol % (max. 25 vol %). In case of lower values the infusion should be supplemented w/ erythrocyte concentrate whole blood.

Child Dose

Renal Dose

Administration

Contra Indications

Existing anaphylactoid reaction.

Precautions

Cardiac insufficiency, fixed HTN, cardiogenic shock.

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Plasma Volume Substitute : Wheals, transient urticarial skin reactions, temporary hypotension, rise in temp &/or shivering.

Mechanism of Action