Procaine hydrochloride + Magnesium chloride + Potassium chloride
Indications
Procaine hydrochloride + Magnesium chloride + Potassium chloride is used for:
Indicated in cardiopulmonary bypass & open-heart surgery to induce ischaemic cardiac arrest.
Adult Dose
Injection
The cold, diluted solution is administered by rapid instillation at a rate of about 300ml/m2 body surface area/ minute, for 3 times initially.
Child Dose
Renal Dose
Administration
Ampoule contents must be diluted before use (20ml is added to 1litre of Ringer solution). The solution is cooled (2-8 degree celsius).
Contra Indications
Pregnancy, Children, Hypersensitivity.
Precautions
Physicians familiar with the cardiac surgery should only use this drug, Monitor ECG continuously during the procedure, Use appropriate equipment.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Procaine hydrochloride + Magnesium chloride + Potassium chloride :
Arrhythmias, Ventricular fibrillation, Myocardial infarction, Delayed recovery, Absence of recovery
Mechanism of Action
It temporarily stops heart for cardiac surgery; induce cardiac arrest using drug and assisted by cold.
Procaine hydrochloride, an anesthetic drug, is indicated for the induction of spinal anesthesia. In addition with a vasoconstrictor, Procaine hydrochloride can promote local hemostasis, increase duration of anesthesia and delay systemic absorption of the drug.