Pseudoepherine + Bromhexin + Chlorpheniramine
Indications
Pseudoepherine + Bromhexin + Chlorpheniramine is used for:
Cough, runny nose, sneezing, itching, watery eyes, sinus congestion caused by allergies, common cold
Adult Dose
Oral
Adult: 1-2 tsf 3-4 times daily
Child Dose
Oral
Child > 12 years: 1-2 tsf 3-4 times daily
Renal Dose
Administration
May be taken with food.
Contra Indications
Hypersensitivity
Precautions
Caution if history of asthma; lung problems (eg, emphysema); heart problems; diabetes; difficulty urinating; an enlarged prostate or other prostate problems; glaucoma; high blood pressure; an overactive thyroid; liver problems (eg, hepatitis) or severe kidney problems; adrenal gland problems (eg, pheochromocytoma); sleep apnea; trouble sleeping.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Pseudoepherine + Bromhexin + Chlorpheniramine :
Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.
Mechanism of Action
Pseudoephedrine is both an α-and β-adrenergic receptor agonist. It causes vasoconstriction via direct stimulation of α-adrenergic receptors of the respiratory mucosa. It also directly stimulates β-adrenergic receptors causing bronchial relaxation, increased heart rate and contractility.
Chlorpheniramine is histamine H1-receptor antagonist in blood vessels, respiratory tract, and gastrointestinal tract.
Bromhexine enhances mucus transport by reducing mucus viscosity and by activating the ciliated epithelium (mucociliary clearance).