Terfenadine

Indications

Terfenadine is used for: Allergic conditions.

Adult Dose

Oral Adult: 60-120 mg/day in the morning or 60 mg twice daily. Max: 120 mg/day.

Child Dose

Oral Child >12 yr and >50 kg: 60-120 mg/day in the morning or 60 mg twice daily. Max: 120 mg/day.

Renal Dose

Administration

Contra Indications

Porphyria.

Precautions

Child and elderly. Avoid in patients with cardiac or significant hepatic disease, electrolyte imbalance, or known or suspected prolongation of the QT interval. Lactation, pregnancy.

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Terfenadine : Anxiety, palpitations, insomnia, mild GI distubances, erythema multiforme and galactorrhoea. Potentially Fatal: Ventricular arrhythmias including torsades de pointes. Palpitations, dizziness, syncope or convulsions may indicate arrhythmias. Hepatitis.

Mechanism of Action

Terfenadine, a piperidine derivative, is a non-sedating H1 receptor antagonist antihistamine.