Coliban 20 Tablet

Dicyclomine
20mg
Lomus Pharmaceutical Pvt. Ltd.
Pack size 1
Dispensing mode
Source
Agent
Retail Price 1.25 NPR

Available as:

Indications

Coliban 20 Tablet is used for: Irritable Bowel Syndrome

Adult Dose

Irritable Bowel Syndrome 20 mg PO q6hr; may increase up to 40 mg q6hr; if efficacy not achieved in 2 weeks or adverse effects require dose <80 mg/day, therapy should be discontinued; safety data not available for doses > 80 mg/day for periods > 2 weeks

Child Dose

Irritable Bowel Syndrome Infants >6 months: 5 mg PO q6-8hr; not to exceed 20 mg/day PO Children: 10 mg PO q6-8hr; not to exceed 40 mg/day PO

Renal Dose

Administration

Take 30-60 minutes before a meal

Contra Indications

Hypersensitivity to dicyclomine or any anticholinergic drugs Closed-angle glaucoma, Myasthenia gravis, Hemorrhage with cardiovascular instability, Paralytic ileus, Breast feeding, Intestinal atony of elderly/debilitated patients, Toxic megacolon, GI obstruction, Obstructive uropathy Severe ulcerative colitis, Reflux esophagitis, Infants aged <6 months (reports of seizure, respiratory failure, death)

Precautions

Caution in renal/hepatic impairment, benign prostatic hyperplasia, congestive heart failure, tachycardia secondary to cardiac insufficiency or thyrotoxicosis, hypertension, coronary artery disease, chronic obstructive pulmonary disease, hiatal hernia, mitral stenosis, brain damage or spastic paralysis in children, salivary secretion disorder, down syndrome, autonimic neuropathy, hyperthyroidism, Tachyarrhythmia; assess before administration, Use caution in patients with mild-moderate ulcerative colitis, Effects may be potentiated when used with other sedative drugs or ethanol, Serious respiratory reactions, CNS symptoms, and deaths reported following administration to infants Lactation: Enters breast milk; contraindicated

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Dicyclomine : >10% Dizziness (40%), Xerostomia (33%), Blurred vision (27%) 1-10% Somnolence (9%), Nervousness (6%), Weakness (7%) Frequency Not Defined Abdominal distension,Confusional state,Cycloplegia,Delirium,Dermatitis,Erythema,Fatigue,Hallucinations,Insomnia,Malaise,Palpitation,Rash,Syncope

Mechanism of Action

Anticholinergic/antispasmodic; no effect on acid secretion, but direct smooth muscle relaxant effects; blocks the action of ACh at parasympathetic sites in smooth muscle, secretory glands, and CNS

Note

Coliban 20 20mg Tablet manufactured by Lomus Pharmaceutical Pvt. Ltd.. Its generic name is Dicyclomine. Coliban 20 is availble in Nepal. Farmaco Nepal drug index information on Coliban 20 Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Dicyclomine :