Danshield Soap
Ketoconazole + Zinc pyrithione Topical
Surbhitam Pharmaceuticals Private Limited
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Available as:
Indications
Danshield Soap is used for:
Dandruff and Seborrhoeic Dermatitis of scalp.
Adult Dose
On wet hair and scalp apply shampoo/lotion and leave for a minute. Rinse with warm water. Repeat procedure and leave shampoo for 3-5 minutes. Rinse with warm water and dry hair.
Child Dose
Renal Dose
Administration
Clean and thoroughly dry the area to be treated. Wash hands before and after applying this medication. Apply it to the affected skin and also to a small amount of the normal skin next to this area
Contra Indications
Hypersensitivity to any ingredient in ketoconazole gel and pyrithione zinc shampoo gel
Precautions
Use this medication on the scalp and skin only. Avoid using in the eyes, nose, or mouth.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Ketoconazole + Zinc pyrithione Topical :
Burning, redness, or dryness of the treated skin may occur.
Mechanism of Action
Ketoconazole interferes w/ biosynthesis of triglycerides and phopholipids by blocking fungal CYP450, thus altering cell membrane permeability in susceptible fungi. It also inhibits other fungal enzymes resulting in the accumulation of toxic concentrations of hydrogen peroxide.
Zinc pyrithione Binds to hair and external skin layers; reduces turnover rate of cells; toxicity nonspecific for epidermal cells; cytostatic agent.
Note
Danshield Soap manufactured by Surbhitam Pharmaceuticals Private Limited. Its generic name is Ketoconazole + Zinc pyrithione Topical. Danshield is availble in Nepal.
Farmaco Nepal drug index information on Danshield Soap is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.