DESTINE Tablet
Desloratadine
5MG
Biogain Remedies Pvt. Ltd.
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| Retail Price | 12.50 NPR |
Indications
DESTINE Tablet is used for:
Itching, Sneezing, Watery eyes, Allergic conditions, Runny nose, Hives, Skin rash, Common cold
Adult Dose
Oral
Allergic conditions
Adult: 5 mg once daily.
Hepatic Impairment: Initially, 5 mg every other day.
Child Dose
Oral
Allergic conditions
Child: 12 years or over : 5 mg once daily.
Child 6-11 years : 2.5 mg once daily.
Child 12 months-5 years : 1.25 mg (2.5 ml syrup) once daily.
Child 6 months-11 months : 1 mg (2 ml syrup) once daily.
Renal Dose
Initially, 5 mg every other day.
Administration
May be taken with or without food.
Contra Indications
Hypersensitivity.
Precautions
Severe renal or hepatic failure; children <6 mth, elderly, epilepsy, pregnancy and lactation.
Lactation: excretion in milk unknown/not recommended
Pregnancy-Lactation
Interactions
Potential increase in plasma concentrations w/ drugs affecting hepatic microsomal enzymes (e.g. azithromycin, cimetidine, erythromycin, fluoxetine, ketoconazole).
Adverse Effects
Side effects of Desloratadine :
>10%
Headache (14%),Fever (12%),Irritability (12%),Diarrhea (15%),Upper respiratory infection (11%),Cough (11%)
1-10%
Dizziness (4%),Somnolence (2%),Dizziness (4%),Fatigue (2%),Erythema (2%),Macupopular rash (3%),Dysmenorrhea (2%),Urinary tract infection (4%),Bronchitis (6%),Epistaxis (3%)
Mechanism of Action
Desloratadine is a long-acting, tricyclic, non-sedating, selective peripheral histamine H1-receptor antagonist which inhibits the release of pro-inflammatory mediators from human mast cells and basophils.
Note
DESTINE 5MG Tablet manufactured by Biogain Remedies Pvt. Ltd.. Its generic name is Desloratadine. DESTINE is availble in Nepal.
Farmaco Nepal drug index information on DESTINE Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.