E Con Tablet

Levonorgestrel
.75mg
Nepal C.R.S.
Pack size 1
Dispensing mode
Source
Agent
Retail Price 80 NPR

Indications

E Con Tablet is used for: Contraception , Emergency contraception , Menopausal hormone replacement therapy , Menorrhagia,

Adult Dose

Oral Emergency contraception Adult: 1.5 mg as soon as possible or within 72 hr of coitus. Alternatively, 750 mcg as soon as possible or within 72 hr of coitus followed by a 2nd dose 12 hr later. Most effective if taken as soon as possible after unprotected intercourse Menopausal hormone replacement therapy Adult: As progestogenic component: 75-250 mcg for 10-12 days of a 28-day cycle. Contraception Adult: Monotherapy: 30 or 37.5 mcg daily.

Child Dose

Renal Dose

Administration

May be taken with or without food.

Contra Indications

Pregnancy, undiagnosed vaginal bleeding, severe arterial disease; liver adenoma, porphyria; after recent evacuation of hydatidiform mole; history of breast cancer; hepatic impairment.

Precautions

Sex-steroid dependent cancer, past ectopic pregnancy, malabsorption syndromes, functional ovarian cysts, active liver disease, recurrent cholestatic jaundice, history of jaundice in pregnancy, CV or renal impairment, DM, asthma, epilepsy, migraine, conditions aggravated by fluid retention, depression and thromboembolism (high doses); lactation.

Pregnancy-Lactation

Interactions

Reduced efficacy with enzyme-inducing drugs; aminoglutethimide. May inhibit ciclosporin metabolism.

Adverse Effects

Side effects of Levonorgestrel : >10% Headache (12%),Acne (15%),Ovarian cysts (13%),Enlarged follicles (12%),Amenorrhea (1-12%),Abdominal pain (12%),Uterine/vaginal bleeding alterations (52%),Intermenstrual bleeding/spotting (23%),Vulvovaginitis (20%),Ectopic pregnancy (≤50%) 1-10% Depression (4%),Migraine (2%),Alopecia (1%),Dysmenorrhea (9%),Menorrhagia (6%),Breast tenderness (3-9%),Pelvic pain (6%),Leukorrhea (5%),Vaginal discharge (4%),Pelvic infection (1%) <1% Angioedema,Cervical perforation,Failed insertion,Sepsis,Uterine bleeding,Device breakage Potentially Fatal: Thrombocytopenia, stroke.

Mechanism of Action

Levonorgestrel, a nortestosterone derivative, is an active isomer of norgestrel. It is a potent inhibitor of ovulation and has androgenic activity.

Note

E Con .75mg Tablet manufactured by Nepal C.R.S.. Its generic name is Levonorgestrel. E Con is availble in Nepal. Farmaco Nepal drug index information on E Con Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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