Available as:
Indications
Epidosin Tablet is used for:
Dysmenorrhoea, Postoperative pain, Visceral spasms, Gastrointestinal tract spasm, Tenesmus, Urinary tract and bile stone colic,
Adult Dose
Oral
Dysmenorrhoea
Adult: Each tablet contains 10 mg valethamate bromide and 325 mg paracetamol. 1 tablet tid.
Postoperative pain
Adult: Each tablet contains 10 mg valethamate bromide and 325 mg paracetamol. 1 tablet tid.
Visceral spasms
Adult: Each tablet contains 10 mg valethamate bromide and 325 mg paracetamol. 1 tablet tid.
Gastrointestinal tract spasm
Adult: Each tablet contains 10 mg valethamate bromide and 325 mg paracetamol. 1 tablet tid.
Tenesmus
Adult: Each tablet contains 10 mg valethamate bromide and 325 mg paracetamol. 1 tablet tid.
Urinary tract and bile stone colic
Adult: Each tablet contains 10 mg valethamate bromide and 325 mg paracetamol. 1 tablet tid.
Parenteral
Dysmenorrhoea
Adult: 8-16 mg daily, via IM or IV inj.
Visceral spasms
Adult: 8-16 mg daily, via IM or IV inj.
Gastrointestinal tract spasm
Adult: 8-16 mg daily, via IM or IV inj.
Urinary tract and bile stone colic
Adult: 8-16 mg daily, via IM or IV inj.
Child Dose
Renal Dose
Administration
Contra Indications
Narrow angle glaucoma, benign prostatic hyperplasia, paralytic ileus, pyloric stenosis, ulcerative colitis, megacolon, tachyarrhythmia. Severe hepatic and renal impairment.
Precautions
May impair ability to drive or operate machinery at high doses.
Pregnancy-Lactation
Interactions
Increased antimuscarinic side effects with drugs with antimuscarinic properties e.g. amantadine, antihistamines, phenothiazide antipsychotics, TCAs. Antagonise GI effects of domperidone, metoclopramide. Delayed gastric emptying reduces absorption of other drugs.
Adverse Effects
Side effects of Valethamate :
Dry mouth, blurring of vision, difficulty in swallowing and talking, constipation, urinary retention, mydriasis, arrhythmias.
Mechanism of Action
A quaternary ammonium anticholinergic with peripheral actions close to those of atropine.
Note
Epidosin 10mg Tablet manufactured by TTK. Its generic name is Valethamate. Epidosin is availble in Nepal.
Farmaco Nepal drug index information on Epidosin Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.