Epidosin Injection

Valethamate
8mg
TTK
Pack size
Dispensing mode
Source
Agent
Retail Price 27.48 NPR

Available as:

Indications

Epidosin Injection is used for: Dysmenorrhoea, Postoperative pain, Visceral spasms, Gastrointestinal tract spasm, Tenesmus, Urinary tract and bile stone colic,

Adult Dose

Oral Dysmenorrhoea Adult: Each tablet contains 10 mg valethamate bromide and 325 mg paracetamol. 1 tablet tid. Postoperative pain Adult: Each tablet contains 10 mg valethamate bromide and 325 mg paracetamol. 1 tablet tid. Visceral spasms Adult: Each tablet contains 10 mg valethamate bromide and 325 mg paracetamol. 1 tablet tid. Gastrointestinal tract spasm Adult: Each tablet contains 10 mg valethamate bromide and 325 mg paracetamol. 1 tablet tid. Tenesmus Adult: Each tablet contains 10 mg valethamate bromide and 325 mg paracetamol. 1 tablet tid. Urinary tract and bile stone colic Adult: Each tablet contains 10 mg valethamate bromide and 325 mg paracetamol. 1 tablet tid. Parenteral Dysmenorrhoea Adult: 8-16 mg daily, via IM or IV inj. Visceral spasms Adult: 8-16 mg daily, via IM or IV inj. Gastrointestinal tract spasm Adult: 8-16 mg daily, via IM or IV inj. Urinary tract and bile stone colic Adult: 8-16 mg daily, via IM or IV inj.

Child Dose

Renal Dose

Administration

Contra Indications

Narrow angle glaucoma, benign prostatic hyperplasia, paralytic ileus, pyloric stenosis, ulcerative colitis, megacolon, tachyarrhythmia. Severe hepatic and renal impairment.

Precautions

May impair ability to drive or operate machinery at high doses.

Pregnancy-Lactation

Interactions

Increased antimuscarinic side effects with drugs with antimuscarinic properties e.g. amantadine, antihistamines, phenothiazide antipsychotics, TCAs. Antagonise GI effects of domperidone, metoclopramide. Delayed gastric emptying reduces absorption of other drugs.

Adverse Effects

Side effects of Valethamate : Dry mouth, blurring of vision, difficulty in swallowing and talking, constipation, urinary retention, mydriasis, arrhythmias.

Mechanism of Action

A quaternary ammonium anticholinergic with peripheral actions close to those of atropine.

Note

Epidosin 8mg Injection manufactured by TTK. Its generic name is Valethamate. Epidosin is availble in Nepal. Farmaco Nepal drug index information on Epidosin Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Valethamate :