Iver DT Tablet

Ivermectin
6mg
Alive Pharmaceutical. Pvt. Ltd.
Pack size 1
Dispensing mode
Source
Agent
Retail Price 22.00 NPR

Indications

Iver DT Tablet is used for: Ascariasis, Strongyloidiasis, Filariasis, Scabies, Onchocerciasis, Gnathostomiasis

Adult Dose

Strongyloidiasis of the Intestinal Tract 15-24 kg: 3 mg PO once 25-35 kg: 6 mg PO once 36-50 kg: 9 mg PO once 51-65 kg: 12 mg PO once 66-79 kg: 15 mg PO once >80 kg: 200 mcg/kg PO once River Blindness (Onchocerciasis) 15-25 kg: 3 mg PO; may repeat in 3-12 mo 26-44 kg: 6 mg PO; may repeat in 3-12 mo 45-64 kg: 9 mg PO; may repeat in 3-12 mo 65-84 kg: 12 mg PO; may repeat in 3-12 mo >85 kg: 150 mcg/kg PO; may repeat in 3-12 mo Scabies Due to Sarcoptes Scabiel Immunocompromised patients: 200 mcg/kg as single dose; may repeat in 14 days if necessary Gnathostoma Spinigerum Gnathostomiasis: 200 mcg/kg as single dose

Child Dose

River Blindness (Onchocerciasis) <15 kg: Safety and efficacy not established 15-25 kg: 3 mg PO; may repeat in 3-12 mo 26-44 kg: 6 mg PO; may repeat in 3-12 mo 45-64 kg: 9 mg PO; may repeat in 3-12 mo 65-84 kg: 12 mg PO; may repeat in 3-12 mo >85 kg: 150 mcg/kg PO; may repeat in 3-12 mo Strongyloidiasis of the Intestinal Tract <15 kg: Safety and efficacy not established 15-24 kg: 3 mg PO once 25-35 kg: 6 mg PO once 36-50 kg: 9 mg PO once 51-65 kg: 12 mg PO once 66-79 kg: 15 mg PO once >80 kg: 200 mcg/kg PO once

Renal Dose

Administration

Should be taken on an empty stomach.

Contra Indications

Hypersensitivity. Pregnancy and lactation. Childn <15 kg body weight.

Precautions

Concurrent Loa loa infection, impaired blood-brain barrier function due to infection. Lactation: Enters breast milk (AAP Committee states compatible with nursing)

Pregnancy-Lactation

Interactions

Bioavailability may be increased by alcohol, levamisole.

Adverse Effects

Side effects of Ivermectin : Diarrhoea, nausea, vomiting, dizziness, pruritus, urticaria, rash, arthralgia, fever, myalgia, asthenia, postural hypotension, tachycardia, oedema, lymphadenopathy, sore throat, cough, headache, somnolence, transient eosinophilia, raised liver enzyme values.

Mechanism of Action

Ivermectin selectively binds and with high affinity to glutamate-gated chloride ion channels, which occur in invertebrate nerve and muscle cells leading to an increase in the permeability of cell membranes to chloride ions with hyperpolarization of the nerve or muscle cell and, ultimately, death of the parasite.

Note

Iver DT 6mg Tablet manufactured by Alive Pharmaceutical. Pvt. Ltd.. Its generic name is Ivermectin. Iver DT is availble in Nepal. Farmaco Nepal drug index information on Iver DT Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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