Liofen Tablet
Baclofen
10mg
Sun Pharmaceutical Industries Ltd.
| Pack size | 1 |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 16.38 NPR |
Available as:
Indications
Liofen Tablet is used for:
Pain, Chronic muscle spasticity, Multiple sclerosis, Spasm, Stiffness, Low back pain
Adult Dose
Oral
Spasticity
Adult: Initially, 5 mg tid for 3 days increased to 10 mg tid for 3 days, then in similar increments and intervals until either 20 mg tid is reached or until desired effect is obtained. Max: 80 mg daily.
Elderly: Initiate with lower doses.
Child Dose
Oral
Spasticity
Child: 0.75-2 mg/kg daily. May initiate with 2.5 mg 4 times daily, increased gradually every 3 days until desired effect is obtained.
Maintenance: 6-10 yr: 30-60 mg daily; 2-6 yr: 20-30 mg daily; 12 mth-2 yr: 10-20 mg daily. Max: >10 yr: 2.5 mg/kg daily.
Renal Dose
Renal impairment: Dose reduction may be required.
Administration
Should be taken with food.
Contra Indications
Hypersensitivity. Active peptic ulcer disease.
Precautions
Cerebrovascular disorders, epilepsy, severe psychotic disorders, confusional states, history of peptic ulcer, resp depression, diabetes (DM), hepatic or renal impairment, elderly, pregnancy. Avoid sudden withdrawal.
Lactation: Enters breast milk in small amounts; not recommended
Pregnancy-Lactation
Interactions
Hypotensive effect may be increased with antihypertensives. Concomittant use with levodopa in Parkinson patients may result in confusion, agitation, hallucinations.
Potentially Fatal: CNS depressants and alcohol may potentiate CNS effects.
Adverse Effects
Side effects of Baclofen :
>10%
Drowsiness, transient (10-63%),Dizziness (5-15%),Nausea (4-12%),Confusion (1-11%)
1-10%
Headache (4-8%),Insomnia (2-7%),Constipation (2-6%),Urinary frequency (2-6%),Fatigue (2-4%)
<1%
Abdominal pain,Ankle edema,Anorexia,Ataxia,Blurred vision,Chest pain,Coordination disorder,Depression,Diarrhea,Dry mouth,Diplopia,Dysarthria,Dyspnea,Dystonia,Enuresis,Euphoria,Excitement,Hallucinations,Hematuria,Hypotension,Impotence,Miosis,Muscle pain,Mydriasis,Nasal congestion,Nocturia,Nystagmus,Palpitation,Paresthesia,Excessive perspiration,Pruritus,Rash,Rigidity,Seizure,Strabismus,Slurred speech,Syncope,Tinnitus,Tremor,Urinary retention,Vomiting,Weight gain
Potentially Fatal: Respiratory or CV depression, seizures.
Mechanism of Action
Baclofen is an antispastic. It inhibits both monosynaptic and polysynaptic reflexes at spinal level.
Note
Liofen 10mg Tablet manufactured by Sun Pharmaceutical Industries Ltd.. Its generic name is Baclofen. Liofen is availble in Nepal.
Farmaco Nepal drug index information on Liofen Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.