Liofen Tablet

Baclofen
10mg
Sun Pharmaceutical Industries Ltd.
Pack size 1
Dispensing mode
Source
Agent
Retail Price 16.38 NPR

Indications

Liofen Tablet is used for: Pain, Chronic muscle spasticity, Multiple sclerosis, Spasm, Stiffness, Low back pain

Adult Dose

Oral Spasticity Adult: Initially, 5 mg tid for 3 days increased to 10 mg tid for 3 days, then in similar increments and intervals until either 20 mg tid is reached or until desired effect is obtained. Max: 80 mg daily. Elderly: Initiate with lower doses.

Child Dose

Oral Spasticity Child: 0.75-2 mg/kg daily. May initiate with 2.5 mg 4 times daily, increased gradually every 3 days until desired effect is obtained. Maintenance: 6-10 yr: 30-60 mg daily; 2-6 yr: 20-30 mg daily; 12 mth-2 yr: 10-20 mg daily. Max: >10 yr: 2.5 mg/kg daily.

Renal Dose

Renal impairment: Dose reduction may be required.

Administration

Should be taken with food.

Contra Indications

Hypersensitivity. Active peptic ulcer disease.

Precautions

Cerebrovascular disorders, epilepsy, severe psychotic disorders, confusional states, history of peptic ulcer, resp depression, diabetes (DM), hepatic or renal impairment, elderly, pregnancy. Avoid sudden withdrawal. Lactation: Enters breast milk in small amounts; not recommended

Pregnancy-Lactation

Interactions

Hypotensive effect may be increased with antihypertensives. Concomittant use with levodopa in Parkinson patients may result in confusion, agitation, hallucinations. Potentially Fatal: CNS depressants and alcohol may potentiate CNS effects.

Adverse Effects

Side effects of Baclofen : >10% Drowsiness, transient (10-63%),Dizziness (5-15%),Nausea (4-12%),Confusion (1-11%) 1-10% Headache (4-8%),Insomnia (2-7%),Constipation (2-6%),Urinary frequency (2-6%),Fatigue (2-4%) <1% Abdominal pain,Ankle edema,Anorexia,Ataxia,Blurred vision,Chest pain,Coordination disorder,Depression,Diarrhea,Dry mouth,Diplopia,Dysarthria,Dyspnea,Dystonia,Enuresis,Euphoria,Excitement,Hallucinations,Hematuria,Hypotension,Impotence,Miosis,Muscle pain,Mydriasis,Nasal congestion,Nocturia,Nystagmus,Palpitation,Paresthesia,Excessive perspiration,Pruritus,Rash,Rigidity,Seizure,Strabismus,Slurred speech,Syncope,Tinnitus,Tremor,Urinary retention,Vomiting,Weight gain Potentially Fatal: Respiratory or CV depression, seizures.

Mechanism of Action

Baclofen is an antispastic. It inhibits both monosynaptic and polysynaptic reflexes at spinal level.

Note

Liofen 10mg Tablet manufactured by Sun Pharmaceutical Industries Ltd.. Its generic name is Baclofen. Liofen is availble in Nepal. Farmaco Nepal drug index information on Liofen Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Baclofen :