Neomercazole 5 Tablet

Carbimazole
5mg
Abbott India Ltd.
Pack size 1
Dispensing mode
Source
Agent
Retail Price 350.82 NPR

Indications

Neomercazole 5 Tablet is used for: Grave's disease, Hyperthyroidism, Diabetic nephropathy, Preparation for thyroidectomy

Adult Dose

Oral Hyperthyroidism, Adjunct to radio-iodine therapy, Grave's disease, Preparation for thyroidectomy Adult: Initially, 20-60 mg daily as a single or divided dose, reduced gradually once euthyroidism is achieved. Maintenance: 5-15 mg daily for at least 1 yr or 18 mth. Hepatic impairment: Severe: Contraindicated.

Child Dose

Oral Hyperthyroidism; Adjunct to radio-iodine therapy; Preparation for thyroidectomy Child: 3-17 yr Initially, 15 mg daily, adjusted according to response.

Renal Dose

Administration

May be taken with or without food. Take consistently w/ or w/o meals.

Contra Indications

Hyperthyroidism due to nodular goitre.

Precautions

Liver diseases, pregnancy, lactation.

Pregnancy-Lactation

Interactions

Increased serum levels of theophylline or may develop toxicity. May enhance the effect of anticoagulants. Potentially Fatal: Increased sensitivity to warfarin in hyperthyroidism and careful control required as patient is rendered euthyroid.

Adverse Effects

Side effects of Carbimazole : Mild leucopaenia, sore throat, mouth ulcers, fever, bruising, malaise; rarely cholestatic jaundice; nephrotic syndrome. Nausea, loss of taste, headache, arthralgia, alopoecia. Potentially Fatal: Agranulocytosis, aplastic anaemia, hypoprothrombinaemia, neutropaenia; hypothyroidism and goitre.

Mechanism of Action

Carbimazole is metabolised to methimazole which is responsible for its antithyroid action. It blocks the production of thyroid hormones by inhibiting thyroid peroxidase.

Note

Neomercazole 5 5mg Tablet manufactured by Abbott India Ltd.. Its generic name is Carbimazole. Neomercazole 5 is availble in Nepal. Farmaco Nepal drug index information on Neomercazole 5 Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Carbimazole :