Oragum Gel

Choline salicylate + Benzalkonium Chloride
Nova Genetica Pvt. Ltd.
Pack size
Dispensing mode
Source
Agent
Retail Price 102.30 NPR

Indications

Oragum Gel is used for: Painful mouth ulcers, glossitis, stomatitis, denture irritation & teething pain.

Adult Dose

Oral prep Adult Rub 1-2 drops gently onto affected areas every 3-4 hr.

Child Dose

Oral prep Childn >6 mth Rub 1-2 drops gently onto affected areas every 3-4 hr.

Renal Dose

Administration

Contra Indications

Haemophilia, haemorrhagic disorders, gout, history of hypersensitivity to salicylates. Severe renal or hepatic impairment; childn <12 yrs. Pregnancy and lactation.

Precautions

Peptic ulcers, errosive gastritis; asthma, allergic disorders; renal and hepatic impairment; dehydrated patients; uncontrolled hypertension; elderly.

Pregnancy-Lactation

Interactions

Increased toxicity of warfarin. Antacids may reduce salicylate effects. Increased risk of GI bleeding when used with corticosteroids.

Adverse Effects

Side effects of Choline salicylate + Benzalkonium Chloride : GI disorders, fatigue, hypersensitivity reactions, skin eruptions, haemolytic anaemia, weakness, dyspnoea; local irritation (rectally); Reye's syndrome. Potentially Fatal: Paroxysmal bronchospasm; hepatotoxicity; renal impairment; thrombocytopenia, iron-deficiency anaemia, occult bleeding, leukopenia; mild chronic salicylate intoxication.

Mechanism of Action

Choline Salicylate is an analgesic for topical application. It's soothes away pain within 3-4 minutes and affects for 3-4 hours. Benzalkonium chloride has been widely used as a broad spectrum anti microbial agent for disinfection, antisepsis and preservation of pharmaceutical products. Benzalkonium chloride exerts its antimicrobial effect through non specific interaction at the bacterial cytoplasmic membrane. Such action increases membrane permeability towards cytoplasmic materials such as amino acids and nucleotides and results eventually in the lysis of the cells.

Note

Oragum Gel manufactured by Nova Genetica Pvt. Ltd.. Its generic name is Choline salicylate + Benzalkonium Chloride. Oragum is availble in Nepal. Farmaco Nepal drug index information on Oragum Gel is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Choline salicylate + Benzalkonium Chloride :