Rogum Gel Gel
Choline salicylate + Benzalkonium Chloride
9% w/v + 0.02 % w/v
Curex Pharmaceuticals Pvt. Ltd.
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Indications
Rogum Gel Gel is used for:
Painful mouth ulcers, glossitis, stomatitis, denture irritation & teething pain.
Adult Dose
Oral prep
Adult
Rub 1-2 drops gently onto affected areas every 3-4 hr.
Child Dose
Oral prep
Childn >6 mth
Rub 1-2 drops gently onto affected areas every 3-4 hr.
Renal Dose
Administration
Contra Indications
Haemophilia, haemorrhagic disorders, gout, history of hypersensitivity to salicylates. Severe renal or hepatic impairment; childn <12 yrs. Pregnancy and lactation.
Precautions
Peptic ulcers, errosive gastritis; asthma, allergic disorders; renal and hepatic impairment; dehydrated patients; uncontrolled hypertension; elderly.
Pregnancy-Lactation
Interactions
Increased toxicity of warfarin. Antacids may reduce salicylate effects. Increased risk of GI bleeding when used with corticosteroids.
Adverse Effects
Side effects of Choline salicylate + Benzalkonium Chloride :
GI disorders, fatigue, hypersensitivity reactions, skin eruptions, haemolytic anaemia, weakness, dyspnoea; local irritation (rectally); Reye's syndrome.
Potentially Fatal: Paroxysmal bronchospasm; hepatotoxicity; renal impairment; thrombocytopenia, iron-deficiency anaemia, occult bleeding, leukopenia; mild chronic salicylate intoxication.
Mechanism of Action
Choline Salicylate is an analgesic for topical application. It's soothes away pain within 3-4 minutes and affects for 3-4 hours.
Benzalkonium chloride has been widely used as a broad spectrum anti microbial agent for disinfection, antisepsis and preservation of pharmaceutical products.
Benzalkonium chloride exerts its antimicrobial effect through non specific interaction at the bacterial cytoplasmic membrane. Such action increases membrane permeability towards cytoplasmic materials such as amino acids and nucleotides and results eventually in the lysis of the cells.
Note
Rogum Gel 9% w/v + 0.02 % w/v Gel manufactured by Curex Pharmaceuticals Pvt. Ltd.. Its generic name is Choline salicylate + Benzalkonium Chloride. Rogum Gel is availble in Nepal.
Farmaco Nepal drug index information on Rogum Gel Gel is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.