Silosin Capsule
Silodosin
4MG
Asian Pharmaceuticals Pvt. Ltd.
| Pack size | 30's |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 20.00 NPR |
Available as:
Indications
Silosin Capsule is used for:
Treating the signs and symptoms of enlarged prostate (benign prostatic hyperplasia [BPH]).
Adult Dose
Benign Prostatic Hyperplasia
Adults
PO 8 mg once daily with a meal.
Hepatic Impairment
Mild-to-moderate impairment (Child-Pugh class A or B): Dose adjustment not necessary
Severe Impairment: (Child-Pugh class C): Contraindicated (not studied)
Child Dose
Renal Dose
Renal Impairment
CrCl <50 mL/min: Dose adjustment not necessary
CrCl 30-50 mL/min: 4 mg PO qDay
CrCl <30 mL/min: Contraindicated
Administration
Contra Indications
Hypersensitivity.
Precautions
Impaired hepatic & renal function. Start treatment w/ a low dose (2 mg/dose).
Pregnancy-Lactation
Interactions
Ketoconazole, digoxin.
Adverse Effects
Side effects of Silodosin :
>10%
Retrograde ejaculation (28%)
1-10%
Diarrhea (3%),Headache (2%),Insomnia ((1-2%),Dizziness (3%),Orthostatic hypotension (3%; increased in patients >65 years),Nasopharyngitis (2%),Nasal congestion (2%),Sinusitis (1-2%)
Mechanism of Action
Selectively blocks postsynaptic alpha-1 adrenoreceptors located in the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra.
Note
Silosin 4MG Capsule manufactured by Asian Pharmaceuticals Pvt. Ltd.. Its generic name is Silodosin. Silosin is availble in Nepal.
Farmaco Nepal drug index information on Silosin Capsule is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.