SILOSIN Capsule

Silodosin
8MG
Asian Pharmaceuticals Pvt. Ltd.
Pack size 10's
Dispensing mode
Source
Agent
Retail Price 35.00 NPR

Available as:

Indications

SILOSIN Capsule is used for: Treating the signs and symptoms of enlarged prostate (benign prostatic hyperplasia [BPH]).

Adult Dose

Benign Prostatic Hyperplasia Adults PO 8 mg once daily with a meal. Hepatic Impairment Mild-to-moderate impairment (Child-Pugh class A or B): Dose adjustment not necessary Severe Impairment: (Child-Pugh class C): Contraindicated (not studied)

Child Dose

Renal Dose

Renal Impairment CrCl <50 mL/min: Dose adjustment not necessary CrCl 30-50 mL/min: 4 mg PO qDay CrCl <30 mL/min: Contraindicated

Administration

Contra Indications

Hypersensitivity.

Precautions

Impaired hepatic & renal function. Start treatment w/ a low dose (2 mg/dose).

Pregnancy-Lactation

Interactions

Ketoconazole, digoxin.

Adverse Effects

Side effects of Silodosin : >10% Retrograde ejaculation (28%) 1-10% Diarrhea (3%),Headache (2%),Insomnia ((1-2%),Dizziness (3%),Orthostatic hypotension (3%; increased in patients >65 years),Nasopharyngitis (2%),Nasal congestion (2%),Sinusitis (1-2%)

Mechanism of Action

Selectively blocks postsynaptic alpha-1 adrenoreceptors located in the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra.

Note

SILOSIN 8MG Capsule manufactured by Asian Pharmaceuticals Pvt. Ltd.. Its generic name is Silodosin. SILOSIN is availble in Nepal. Farmaco Nepal drug index information on SILOSIN Capsule is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Silodosin :