Urtizen Tablet

Hydroxyzine Hydrochloride
25mg
Maruti Pharma Pvt. Ltd.
Pack size 10's
Dispensing mode
Source
Agent
Retail Price 4.50 NPR

Indications

Urtizen Tablet is used for: Pruritus, Allergic conditions, Generalized anxiety disorder, Psychoneurosis, Chronic urticaria, Atopic or contact dermatoses, Pre- or post-operative sedation

Adult Dose

Oral Short-term management of anxiety Adult: 50-100 mg 4 times daily. Pruritus in acute and chronic urticaria and dermatosis Adult: Initially, 25 mg at night increased if required up to 25 mg 3-4 times daily. Adjunct to pre- or post-operative sedation Adult: 50-100 mg. Hepatic impairment: Reduce total daily dose by 33%.

Child Dose

Oral Pruritus in acute and chronic urticaria and dermatosis Child: 6 mth to 6 yr Initially, 5-15 mg/day, increased to 50 mg/day in divided doses; >6 yr Initially, 15-25 mg/day, increased up to 50-100 mg/day in divided doses. Adjunct to pre- or post-operative sedation Child: 600 mcg/kg. Hepatic impairment: Reduce total daily dose by 33%.

Renal Dose

Renal Impairment >50 mL/min: Dose adjustment not necessary <50 mL/min: Administer 50% normal dose

Administration

May be taken with or without food.

Contra Indications

Porphyria, neonates, pregnancy, lactation.

Precautions

Renal and hepatic impairment; narrow-angle glaucoma; epilepsy; prostatic hypertrophy; bladder neck obstruction; asthma; COPD. May impair ability to drive or operate machinery. Lactation: Excretion in milk unknown; use with caution

Pregnancy-Lactation

Interactions

Additive or may potentiate CNS depressant effects of opiates or other analgesics, barbiturates or other sedatives, and anaesth. MAOIs and TCAs potentiate antimuscarinic effects.

Adverse Effects

Side effects of Hydroxyzine Hydrochloride : Dizziness, ataxia, fatigue, drowsiness, hallucination, seizure, dry mouth, nervousness, xerostomia, involuntary movements, slurred speech, headache, paraesthesia, tremor, blurred vision, resp depression, pruritus, rash, urticaria, allergic reaction.

Mechanism of Action

Hydroxyzine, a piperazine derivative, blocks histamine H1-receptors on effector cells of the GI tract, blood vessels and resp tract. It is a sedating antihistamine w/ antimuscarinic and significant sedative properties. It also possesses skeletal muscle relaxing, bronchodilator, antiemetic and analgesic properties.

Note

Urtizen 25mg Tablet manufactured by Maruti Pharma Pvt. Ltd.. Its generic name is Hydroxyzine Hydrochloride. Urtizen is availble in Nepal. Farmaco Nepal drug index information on Urtizen Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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