Cosmelite-GM Cream

Clobetasol + Gentamicin + Miconazole Topical
0.05% + 0.1% + 2%
Maruti Pharma Pvt. Ltd.
Pack size
Dispensing mode
Source
Agent
Retail Price 40.00 NPR

Indications

Cosmelite-GM Cream is used for: Corticosteriod-responsive dermatoses w/ secondary infection by bacteria & fungus.

Adult Dose

Topical/Cutaneous Corticosteriod-responsive dermatoses w/ secondary infection Adult: Cream/Oint: Apply gently to the affected area 2-3 times daily.

Child Dose

Corticosteriod-responsive dermatoses w/ secondary infection Child > 12 yrs: Cream/Oint: Apply gently to the affected area 2-3 times daily.

Renal Dose

Administration

Contra Indications

Hypersensitivity. Childn <12 yrs. Long-term treatment of ulcerative conditions, rosacea, pruritus; presence of acute infections.

Precautions

Glaucoma; hypothyroidism; hepatic failure, renal impairment; psychoses; childn and elderly. Should not enter eyes.

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Clobetasol + Gentamicin + Miconazole Topical : Perioral dermatitis, striae esp in flexures. Dermal and epidermal atrophy esp on the face, steroid purpura, erythema, pruritus, photosensitivity, irritation, burning, contact dermatitis.

Mechanism of Action

Clobetasol is a very potent corticosteroid used in short-term treatment of various inflammatory skin conditions. Gentamicin interferes w/ bacterial protein synthesis by binding to 30S and 50S ribosomal subunits resulting in a defective bacterial cell membrane. Miconazole inhibits ergosterol synthesis thus damaging fungal cell wall membrane and increases its permeability, allowing leakage of nutrients.

Note

Cosmelite-GM 0.05% + 0.1% + 2% Cream manufactured by Maruti Pharma Pvt. Ltd.. Its generic name is Clobetasol + Gentamicin + Miconazole Topical. Cosmelite-GM is availble in Nepal. Farmaco Nepal drug index information on Cosmelite-GM Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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