Cosmelite-GM Cream
Clobetasol + Gentamicin + Miconazole Topical
0.05% + 0.1% + 2%
Maruti Pharma Pvt. Ltd.
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| Retail Price | 40.00 NPR |
Indications
Cosmelite-GM Cream is used for:
Corticosteriod-responsive dermatoses w/ secondary infection by bacteria & fungus.
Adult Dose
Topical/Cutaneous
Corticosteriod-responsive dermatoses w/ secondary infection
Adult: Cream/Oint: Apply gently to the affected area 2-3 times daily.
Child Dose
Corticosteriod-responsive dermatoses w/ secondary infection
Child > 12 yrs: Cream/Oint: Apply gently to the affected area 2-3 times daily.
Renal Dose
Administration
Contra Indications
Hypersensitivity. Childn <12 yrs. Long-term treatment of ulcerative conditions, rosacea, pruritus; presence of acute infections.
Precautions
Glaucoma; hypothyroidism; hepatic failure, renal impairment; psychoses; childn and elderly. Should not enter eyes.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Clobetasol + Gentamicin + Miconazole Topical :
Perioral dermatitis, striae esp in flexures. Dermal and epidermal atrophy esp on the face, steroid purpura, erythema, pruritus, photosensitivity, irritation, burning, contact dermatitis.
Mechanism of Action
Clobetasol is a very potent corticosteroid used in short-term treatment of various inflammatory skin conditions.
Gentamicin interferes w/ bacterial protein synthesis by binding to 30S and 50S ribosomal subunits resulting in a defective bacterial cell membrane.
Miconazole inhibits ergosterol synthesis thus damaging fungal cell wall membrane and increases its permeability, allowing leakage of nutrients.
Note
Cosmelite-GM 0.05% + 0.1% + 2% Cream manufactured by Maruti Pharma Pvt. Ltd.. Its generic name is Clobetasol + Gentamicin + Miconazole Topical. Cosmelite-GM is availble in Nepal.
Farmaco Nepal drug index information on Cosmelite-GM Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.