Solbet GM Cream
Clobetasol + Gentamicin + Miconazole Topical
Deurali Janta Pharmaceuticals Pvt. Ltd.
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| Retail Price | 55.00 NPR |
Indications
Solbet GM Cream is used for:
Corticosteriod-responsive dermatoses w/ secondary infection by bacteria & fungus.
Adult Dose
Topical/Cutaneous
Corticosteriod-responsive dermatoses w/ secondary infection
Adult: Cream/Oint: Apply gently to the affected area 2-3 times daily.
Child Dose
Corticosteriod-responsive dermatoses w/ secondary infection
Child > 12 yrs: Cream/Oint: Apply gently to the affected area 2-3 times daily.
Renal Dose
Administration
Contra Indications
Hypersensitivity. Childn <12 yrs. Long-term treatment of ulcerative conditions, rosacea, pruritus; presence of acute infections.
Precautions
Glaucoma; hypothyroidism; hepatic failure, renal impairment; psychoses; childn and elderly. Should not enter eyes.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Clobetasol + Gentamicin + Miconazole Topical :
Perioral dermatitis, striae esp in flexures. Dermal and epidermal atrophy esp on the face, steroid purpura, erythema, pruritus, photosensitivity, irritation, burning, contact dermatitis.
Mechanism of Action
Clobetasol is a very potent corticosteroid used in short-term treatment of various inflammatory skin conditions.
Gentamicin interferes w/ bacterial protein synthesis by binding to 30S and 50S ribosomal subunits resulting in a defective bacterial cell membrane.
Miconazole inhibits ergosterol synthesis thus damaging fungal cell wall membrane and increases its permeability, allowing leakage of nutrients.
Note
Solbet GM Cream manufactured by Deurali Janta Pharmaceuticals Pvt. Ltd.. Its generic name is Clobetasol + Gentamicin + Miconazole Topical. Solbet GM is availble in Nepal.
Farmaco Nepal drug index information on Solbet GM Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.